Diabetes and chemotherapy

I am diabetic. Are there extra risks if I have chemotherapy?

If you are diabetic, you need to eat regularly to keep your blood sugar stable. Most people with diabetes are used to juggling their need for food with their diabetes medicines. Chemotherapy can make you feel sick or be sick. You may not want to eat and so this can be a problem. If you can't eat, your blood sugar could drop too low, causing faintness, sweating and coma. This is called a hypoglycaemic attack.

There are two different types of diabetes and depending on which type you have will alter how you manage it. If you have

  • Type 1 – you need to have regular insulin injections or an insulin pump
  • Type 2 – you may be able to control it with either diet or with a combination of diet and tablets – although there are some people with type 2 who need to have insulin injections

You and your doctor may need to plan a bit more carefully than would be necessary if you weren’t diabetic. Sometimes steroids are used with chemotherapy combinations and these may upset your sugar balance. It may be a good idea for you and your cancer doctor to talk to your diabetes specialist. 

If you control your diabetes with diet or tablets it should be possible to manage it during chemotherapy without too many problems. Discuss the options with your doctor first, but it may be suggested that you don’t take your diabetes tablets on chemotherapy days, for example.

If you are dependent on insulin injections, your doctor may suggest that you have the first course of chemotherapy in hospital so that the nurses can keep an eye on you. Then, if you need sugar quickly, it can be given through a drip rather than by mouth. It is possible for you to have insulin and sugar solution (dextrose) given together through a drip in hospital. The insulin dose is based on hourly or 2 hourly blood sugar tests. But this is unlikely to be needed for most people. If you are unable to eat your normal diet when you are at home, you may find you need to measure your blood sugar a bit more often than you usually would. 

You may lose your appetite and have to make an effort to have something to eat regularly. Also, you may feel sick because of your chemotherapy drugs. But there are very good anti sickness drugs available that can help. It is important that you have good nutrition. Your doctor can prescribe you meals in a drink. They are rich in calories and you can sip them through the day. There are many different brands, including Complan, Fresubin, and Build Up. 

As diabetes can affect your body's ability to fight infection you may also be at slightly higher risk during chemotherapy than people who are not diabetic. So you will need to look out for signs of infection, such as a high temperature, and contact your doctor or cancer centre immediately.