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A study looking at magnetic resonance imaging (MRI) scans to assess Hodgkin's lymphoma in children and young people - MELT

A study looking at using a new type of MRI scan to assess Hodgkin’s lymphoma and its response to treatment in children and young people.  This study is funded by Cancer Research UK.

The study is for children and young people up to and including the age of 18. We use the term 'you' in this summary, but of course if you are a parent, we are referring to your child.

Hodgkin’s lymphoma is a cancer of the lymphatic system.  It can start in many parts of the body including the lymph nodes, spleen, bone marrow, blood or other organs of the body.  

Doctors will often use a CT scan, PET scan, MRI scan and ultrasound scan to find out where the Hodgkin’s lymphoma is.  They will also use these scans to find out how well it has responded after treatment. The researchers want to compare the new type of MRI scan to these scans.  

The aim of this study is to find out how good the new type of MRI scan is at assessing Hodgkin’s lymphoma and its response to treatment.

Recruitment

Start 26/09/2011
End 26/03/2014

Phase

Other

Who can enter

You may be able to enter this trial if you

  • Have Hodgkin’s lymphoma
  • Are taking part in the Euronet PHL-C1 trial or LP1 trial OR are to have chemotherapy according to the Euronet trials – your doctor can advise about this
  • Are 6 to 18 years old

You cannot enter this trial if you

  • Are not able to have an MRI scan - if you have certain types of metal surgical clips or plates in your body, or a pacemaker for example
  • Have had cancer before
  • Are pregnant or breastfeeding

Trial design

This study will recruit 55 children and young people who attend the University College London Hospital.  

You will have the new type of MRI scan as well as the standard scans before and after your treatment.  The researchers will then compare these MRI scans with your standard scans to see which is better.

Hospital visits

There are no extra hospital visits if you take part in this trial.  But the new type of MRI scan will take about 1 hour to do each time.

Side effects

You may have a reaction to the injection for the scan.  This could include sweating, rash and difficulty breathing.

Location of trial

  • London

For more information

The Information Nurses
Cancer Research UK
Angel Building
407 St John Street
London
EC1V 4AD

Tel: 0808 800 4040
Email: cancer.info@cancer.org.uk

Please note: we cannot help you to join a specific trial. Unless we state otherwise in this trial summary, you must go through your own doctor.

Chief Investigator

Professor Stuart Taylor

Supported by

Cancer Research UK
National Cancer Research Network (NCRN)
University College London (UCL)